Search Page
Save citations to file
Email citations
Send citations to clipboard
Add to Collections
Add to My Bibliography
Create a file for external citation management software
Your saved search
Your RSS Feed
Filters
Results by year
Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2021 | 2 |
2022 | 2 |
2023 | 1 |
2024 | 0 |
Search Results
5 results
Results by year
Filters applied: . Clear all
It looks like you are searching for an author.
Results are currently sorted by Best Match. To see the newest results first,
change the sort order to Most Recent.
Page 1
AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells.
Cell Rep. 2023 May 30;42(5):112536. doi: 10.1016/j.celrep.2023.112536. Epub 2023 May 20.
Cell Rep. 2023.
PMID: 37210723
Free PMC article.
Discovery of Potent, Selective, and In Vivo Efficacious AKT Kinase Protein Degraders via Structure-Activity Relationship Studies.
Yu X, Xu J, Shen Y, Cahuzac KM, Park KS, Dale B, Liu J, Parsons RE, Jin J.
Yu X, et al. Among authors: cahuzac km.
J Med Chem. 2022 Feb 24;65(4):3644-3666. doi: 10.1021/acs.jmedchem.1c02165. Epub 2022 Feb 4.
J Med Chem. 2022.
PMID: 35119851
Free PMC article.
Item in Clipboard
Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders.
Yu X, Xu J, Xie L, Wang L, Shen Y, Cahuzac KM, Chen X, Liu J, Parsons RE, Jin J.
Yu X, et al. Among authors: cahuzac km.
J Med Chem. 2021 Dec 23;64(24):18054-18081. doi: 10.1021/acs.jmedchem.1c01476. Epub 2021 Dec 2.
J Med Chem. 2021.
PMID: 34855399
Free PMC article.
Item in Clipboard
Novel Allosteric Inhibitor-Derived AKT Proteolysis Targeting Chimeras (PROTACs) Enable Potent and Selective AKT Degradation in KRAS/BRAF Mutant Cells.
Yu X, Xu J, Cahuzac KM, Xie L, Shen Y, Chen X, Liu J, Parsons RE, Jin J.
Yu X, et al. Among authors: cahuzac km.
J Med Chem. 2022 Oct 27;65(20):14237-14260. doi: 10.1021/acs.jmedchem.2c01454. Epub 2022 Oct 5.
J Med Chem. 2022.
PMID: 36197750
Free PMC article.
Item in Clipboard
AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway-Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B.
Xu J, Yu X, Martin TC, Bansal A, Cheung K, Lubin A, Stratikopoulos E, Cahuzac KM, Wang L, Xie L, Zhou R, Shen Y, Wu X, Yao S, Qiao R, Poulikakos PI, Chen X, Liu J, Jin J, Parsons R.
Xu J, et al. Among authors: cahuzac km.
Cancer Discov. 2021 Dec 1;11(12):3064-3089. doi: 10.1158/2159-8290.CD-20-0815.
Cancer Discov. 2021.
PMID: 34301793
Free PMC article.
Item in Clipboard
Cite
Cite